node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GOX1820 | accA | GOX1820 | GOX1791 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | Acetyl-CoA carboxylase, carboxyl transferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.712 |
GOX1820 | fabZ | GOX1820 | GOX1821 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.986 |
GOX1820 | lpxA | GOX1820 | GOX1822 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.934 |
GOX1820 | lpxC | GOX1820 | GOX0165 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.979 |
GOX1990 | GOX2039 | GOX1990 | GOX2039 | Enoyl-[acyl-carrier-protein] reductase [NADH]. | Malonyl-CoA-[acyl-carrier-protein] transacylase. | 0.988 |
GOX1990 | GOX2040 | GOX1990 | GOX2040 | Enoyl-[acyl-carrier-protein] reductase [NADH]. | 3-Oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.909 |
GOX1990 | GOX2042 | GOX1990 | GOX2042 | Enoyl-[acyl-carrier-protein] reductase [NADH]. | 3-Oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.981 |
GOX1990 | accA | GOX1990 | GOX1791 | Enoyl-[acyl-carrier-protein] reductase [NADH]. | Acetyl-CoA carboxylase, carboxyl transferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.785 |
GOX1990 | acpP | GOX1990 | GOX2041 | Enoyl-[acyl-carrier-protein] reductase [NADH]. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.899 |
GOX1990 | fabH | GOX1990 | GOX0115 | Enoyl-[acyl-carrier-protein] reductase [NADH]. | 3-Oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.776 |
GOX1990 | fabZ | GOX1990 | GOX1821 | Enoyl-[acyl-carrier-protein] reductase [NADH]. | (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.969 |
GOX2039 | GOX1990 | GOX2039 | GOX1990 | Malonyl-CoA-[acyl-carrier-protein] transacylase. | Enoyl-[acyl-carrier-protein] reductase [NADH]. | 0.988 |
GOX2039 | GOX2040 | GOX2039 | GOX2040 | Malonyl-CoA-[acyl-carrier-protein] transacylase. | 3-Oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.995 |
GOX2039 | GOX2042 | GOX2039 | GOX2042 | Malonyl-CoA-[acyl-carrier-protein] transacylase. | 3-Oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.999 |
GOX2039 | accA | GOX2039 | GOX1791 | Malonyl-CoA-[acyl-carrier-protein] transacylase. | Acetyl-CoA carboxylase, carboxyl transferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.958 |
GOX2039 | acpP | GOX2039 | GOX2041 | Malonyl-CoA-[acyl-carrier-protein] transacylase. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.994 |
GOX2039 | fabH | GOX2039 | GOX0115 | Malonyl-CoA-[acyl-carrier-protein] transacylase. | 3-Oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.999 |
GOX2039 | fabZ | GOX2039 | GOX1821 | Malonyl-CoA-[acyl-carrier-protein] transacylase. | (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.963 |
GOX2040 | GOX1990 | GOX2040 | GOX1990 | 3-Oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Enoyl-[acyl-carrier-protein] reductase [NADH]. | 0.909 |
GOX2040 | GOX2039 | GOX2040 | GOX2039 | 3-Oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Malonyl-CoA-[acyl-carrier-protein] transacylase. | 0.995 |