STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_1D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family (225 aa)    
Predicted Functional Partners:
DM42_3221
Tartro_sem_red: 2-hydroxy-3-oxopropionate reductase
 
 
 0.923
glcE
annotation not available
 
  
 0.918
Gph
Phosphoglycolate phosphatase, bacterial; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress
 
 
  0.915
DM42_3173
Glycerate kinase family protein; Belongs to the glycerate kinase type-1 family
  
 
  0.913
DM42_6037
HAD-SF-IA-v1: HAD hydrolase, IA, variant 1 family protein
 
 
  0.913
eda
Eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein
   
 0.912
aceB
Belongs to the malate synthase family
   
 
 0.910
glcB
Malate synthase g; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA
   
 
 0.910
hyi
Hydroxypyruvate isomerase; Belongs to the hyi family
  
 
 0.909
aceA
Isocit_lyase: isocitrate lyase
     
 0.908
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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