node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DM42_1079 | DM42_1082 | DM42_1079 | DM42_1082 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein | annotation not available | 0.788 |
DM42_1079 | folK | DM42_1079 | DM42_1081 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein | folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase | 0.854 |
DM42_1079 | hda | DM42_1079 | DM42_1078 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein | Dnaa regulatory inactivator hda; Belongs to the DnaA family | 0.848 |
DM42_1079 | pcnB | DM42_1079 | DM42_1080 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein | Poly(a) polymerase family protein; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control | 0.909 |
DM42_1079 | purM | DM42_1079 | DM42_1077 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein | purM: phosphoribosylformylglycinamidine cyclo-ligase | 0.528 |
DM42_1082 | DM42_1079 | DM42_1082 | DM42_1079 | annotation not available | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein | 0.788 |
DM42_1082 | dnaN | DM42_1082 | DM42_1785 | annotation not available | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | 0.412 |
DM42_1082 | folK | DM42_1082 | DM42_1081 | annotation not available | folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase | 0.978 |
DM42_1082 | hda | DM42_1082 | DM42_1078 | annotation not available | Dnaa regulatory inactivator hda; Belongs to the DnaA family | 0.776 |
DM42_1082 | pcnB | DM42_1082 | DM42_1080 | annotation not available | Poly(a) polymerase family protein; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control | 0.820 |
DM42_1082 | purM | DM42_1082 | DM42_1077 | annotation not available | purM: phosphoribosylformylglycinamidine cyclo-ligase | 0.448 |
DM42_827 | dnaN | DM42_827 | DM42_1785 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | 0.997 |
DM42_827 | hda | DM42_827 | DM42_1078 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Dnaa regulatory inactivator hda; Belongs to the DnaA family | 0.728 |
DM42_827 | polA | DM42_827 | DM42_4183 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.844 |
dnaB | dnaN | DM42_3231 | DM42_1785 | Replicative dna helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | 0.816 |
dnaB | hda | DM42_3231 | DM42_1078 | Replicative dna helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | Dnaa regulatory inactivator hda; Belongs to the DnaA family | 0.649 |
dnaB | polA | DM42_3231 | DM42_4183 | Replicative dna helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.899 |
dnaN | DM42_1082 | DM42_1785 | DM42_1082 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | annotation not available | 0.412 |
dnaN | DM42_827 | DM42_1785 | DM42_827 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | 0.997 |
dnaN | dnaB | DM42_1785 | DM42_3231 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | Replicative dna helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 0.816 |