hda protein (Burkholderia cepacia) - STRING interaction network

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Score

hda

dnaA_homol_Hda- DnaA regulatory inactivator Hda; Belongs to the DnaA family (244 aa)

Predicted Functional Partners:

pcnB

0.921

folK

0.864

WI67_03565

0.848

dnaN

0.840

WL94_21710

0.776

dnaA

0.705

purM

0.694

WI67_04835

0.678

upp

0.672

WL94_21715

0.639

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WI67_03565	WL94_21710	DM42_1079	DM42_1082	HAD-SF-IB- HAD phosphoserine phosphatase-like hydrolase, IB family protein	annotation not available	0.788
WI67_03565	WL94_21715	DM42_1079	DM42_1083	HAD-SF-IB- HAD phosphoserine phosphatase-like hydrolase, IB family protein	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family	0.643
WI67_03565	folK	DM42_1079	DM42_1081	HAD-SF-IB- HAD phosphoserine phosphatase-like hydrolase, IB family protein	folK- 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	0.854
WI67_03565	hda	DM42_1079	DM42_1078	HAD-SF-IB- HAD phosphoserine phosphatase-like hydrolase, IB family protein	dnaA_homol_Hda- DnaA regulatory inactivator Hda; Belongs to the DnaA family	0.848
WI67_03565	pcnB	DM42_1079	DM42_1080	HAD-SF-IB- HAD phosphoserine phosphatase-like hydrolase, IB family protein	Poly(A) polymerase I; Adds poly(A) tail to the 3’ end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	0.909
WI67_03565	purM	DM42_1079	DM42_1077	HAD-SF-IB- HAD phosphoserine phosphatase-like hydrolase, IB family protein	purM- phosphoribosylformylglycinamidine cyclo-ligase	0.528
WI67_04835	dnaA	DM42_827	DM42_1786	Dnaq- exonuclease, DNA polymerase III, epsilon subunit family domain protein	Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box)- 5’-TTATC[CA]A[CA]A-3’. DnaA binds to ATP and to acidic phospholipids	0.596
WI67_04835	dnaN	DM42_827	DM42_1785	Dnaq- exonuclease, DNA polymerase III, epsilon subunit family domain protein	Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...]	0.963
WI67_04835	hda	DM42_827	DM42_1078	Dnaq- exonuclease, DNA polymerase III, epsilon subunit family domain protein	dnaA_homol_Hda- DnaA regulatory inactivator Hda; Belongs to the DnaA family	0.678
WL94_21710	WI67_03565	DM42_1082	DM42_1079	annotation not available	HAD-SF-IB- HAD phosphoserine phosphatase-like hydrolase, IB family protein	0.788
WL94_21710	WL94_21715	DM42_1082	DM42_1083	annotation not available	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family	0.735
WL94_21710	dnaN	DM42_1082	DM42_1785	annotation not available	Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...]	0.430
WL94_21710	folK	DM42_1082	DM42_1081	annotation not available	folK- 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	0.978
WL94_21710	hda	DM42_1082	DM42_1078	annotation not available	dnaA_homol_Hda- DnaA regulatory inactivator Hda; Belongs to the DnaA family	0.776
WL94_21710	pcnB	DM42_1082	DM42_1080	annotation not available	Poly(A) polymerase I; Adds poly(A) tail to the 3’ end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	0.821
WL94_21710	purM	DM42_1082	DM42_1077	annotation not available	purM- phosphoribosylformylglycinamidine cyclo-ligase	0.448
WL94_21715	WI67_03565	DM42_1083	DM42_1079	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family	HAD-SF-IB- HAD phosphoserine phosphatase-like hydrolase, IB family protein	0.643
WL94_21715	WL94_21710	DM42_1083	DM42_1082	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family	annotation not available	0.735
WL94_21715	folK	DM42_1083	DM42_1081	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family	folK- 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	0.935
WL94_21715	hda	DM42_1083	DM42_1078	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family	dnaA_homol_Hda- DnaA regulatory inactivator Hda; Belongs to the DnaA family	0.639

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