STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_1116Lysr family transcriptional regulator, hydrogen peroxide-inducible genes activator; Belongs to the LysR transcriptional regulatory family (319 aa)    
Predicted Functional Partners:
katG
Catalase/peroxidase hpi; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity
     
 0.784
recG
Atp-dependent dna helicase recg; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA)
  
  
 0.728
soxR
Merr family transcriptional regulator, redox-sensitive transcriptional activator soxr; soxR: redox-sensitive transcriptional activator SoxR
    
 
 0.646
rpoS
Rna polymerase nonessential primary-like sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response
      
 0.595
ahpF
ahpF: alkyl hydroperoxide reductase subunit F
     
 0.578
gor
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione
     
 0.573
DM42_1111
annotation not available
     
 0.559
queA
S-adenosylmethionine:trna ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
  
    0.490
DM42_1175
Lysr family transcriptional regulator, hypochlorite-specific transcription factor hypt; Belongs to the LysR transcriptional regulatory family
  
   
 0.477
DM42_1115
Conserved hypothetical protein
       0.476
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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