node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DM42_657 | DM42_827 | DM42_657 | DM42_827 | Uvra: excinuclease ABC subunit A | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | 0.933 |
DM42_657 | UvrB | DM42_657 | DM42_670 | Uvra: excinuclease ABC subunit A | Excinuclease abc subunit b; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.979 |
DM42_657 | recA | DM42_657 | DM42_2420 | Uvra: excinuclease ABC subunit A | Recombination protein reca; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage | 0.541 |
DM42_657 | recR | DM42_657 | DM42_3275 | Uvra: excinuclease ABC subunit A | Recombination protein recr; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO | 0.540 |
DM42_657 | ruvA | DM42_657 | DM42_1153 | Uvra: excinuclease ABC subunit A | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB | 0.896 |
DM42_657 | ruvB | DM42_657 | DM42_1154 | Uvra: excinuclease ABC subunit A | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing | 0.901 |
DM42_657 | ruvC | DM42_657 | DM42_1152 | Uvra: excinuclease ABC subunit A | Crossover junction endodeoxyribonuclease ruvc; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group | 0.865 |
DM42_657 | uvrA | DM42_657 | DM42_2291 | Uvra: excinuclease ABC subunit A | Excinuclease abc subunit a; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate | 0.821 |
DM42_657 | uvrB | DM42_657 | DM42_2857 | Uvra: excinuclease ABC subunit A | Excinuclease abc subunit b; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.977 |
DM42_657 | uvrC | DM42_657 | DM42_683 | Uvra: excinuclease ABC subunit A | Excinuclease abc subunit c; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision | 0.949 |
DM42_827 | DM42_657 | DM42_827 | DM42_657 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Uvra: excinuclease ABC subunit A | 0.933 |
DM42_827 | UvrB | DM42_827 | DM42_670 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Excinuclease abc subunit b; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.975 |
DM42_827 | recA | DM42_827 | DM42_2420 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Recombination protein reca; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage | 0.793 |
DM42_827 | recR | DM42_827 | DM42_3275 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Recombination protein recr; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO | 0.724 |
DM42_827 | ruvA | DM42_827 | DM42_1153 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB | 0.941 |
DM42_827 | ruvB | DM42_827 | DM42_1154 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing | 0.943 |
DM42_827 | ruvC | DM42_827 | DM42_1152 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Crossover junction endodeoxyribonuclease ruvc; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group | 0.937 |
DM42_827 | uvrA | DM42_827 | DM42_2291 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Excinuclease abc subunit a; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate | 0.933 |
DM42_827 | uvrB | DM42_827 | DM42_2857 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Excinuclease abc subunit b; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.975 |
UvrB | DM42_657 | DM42_670 | DM42_657 | Excinuclease abc subunit b; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | Uvra: excinuclease ABC subunit A | 0.979 |