STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proACatalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. (423 aa)    
Predicted Functional Partners:
proB
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
 
 0.999
putA
Oxidizes proline to glutamate for use as a carbon and nitrogen source
  
 
 0.964
DM42_1419
annotation not available
  
  
 0.938
proC
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
 
 
 0.906
astE
Transforms N(2)-succinylglutamate into succinate and glutamate
     
 0.901
glnA
glnA: glutamine synthetase, type I
  
 
 0.873
gltD
annotation not available
 
  
 0.869
gdhA
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.856
DM42_2016
Belongs to the glutamine synthetase family.
  
 
 0.849
puuA_3
Belongs to the glutamine synthetase family.
  
 
 0.849
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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