node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AroQ | DM42_5759 | DM42_5472 | DM42_5759 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate | Salicylate biosynthesis isochorismate synthase; Isochor_syn: isochorismate synthase family protein | 0.843 |
AroQ | aroB | DM42_5472 | DM42_1428 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) | 0.955 |
AroQ | aroE | DM42_5472 | DM42_1229 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 0.936 |
AroQ | aroK | DM42_5472 | DM42_1429 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate | Shikimate kinase family protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate | 0.721 |
AroQ | aroQ | DM42_5472 | DM42_1235 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate | 0.809 |
DM42_1230 | aroA | DM42_1230 | DM42_782 | annotation not available | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate | 0.410 |
DM42_1230 | aroE | DM42_1230 | DM42_1229 | annotation not available | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 0.919 |
DM42_1230 | mtgA | DM42_1230 | DM42_1228 | annotation not available | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors | 0.897 |
DM42_5759 | AroQ | DM42_5759 | DM42_5472 | Salicylate biosynthesis isochorismate synthase; Isochor_syn: isochorismate synthase family protein | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate | 0.843 |
DM42_5759 | aroA | DM42_5759 | DM42_782 | Salicylate biosynthesis isochorismate synthase; Isochor_syn: isochorismate synthase family protein | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate | 0.426 |
DM42_5759 | aroB | DM42_5759 | DM42_1428 | Salicylate biosynthesis isochorismate synthase; Isochor_syn: isochorismate synthase family protein | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) | 0.516 |
DM42_5759 | aroC | DM42_5759 | DM42_240 | Salicylate biosynthesis isochorismate synthase; Isochor_syn: isochorismate synthase family protein | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system | 0.918 |
DM42_5759 | aroE | DM42_5759 | DM42_1229 | Salicylate biosynthesis isochorismate synthase; Isochor_syn: isochorismate synthase family protein | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 0.859 |
DM42_5759 | aroQ | DM42_5759 | DM42_1235 | Salicylate biosynthesis isochorismate synthase; Isochor_syn: isochorismate synthase family protein | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate | 0.843 |
aroA | DM42_1230 | DM42_782 | DM42_1230 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate | annotation not available | 0.410 |
aroA | DM42_5759 | DM42_782 | DM42_5759 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate | Salicylate biosynthesis isochorismate synthase; Isochor_syn: isochorismate synthase family protein | 0.426 |
aroA | aroB | DM42_782 | DM42_1428 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) | 0.965 |
aroA | aroC | DM42_782 | DM42_240 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system | 0.987 |
aroA | aroE | DM42_782 | DM42_1229 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 0.873 |
aroA | aroK | DM42_782 | DM42_1429 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate | Shikimate kinase family protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate | 0.975 |