| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DM42_1235 | WI67_30635 | DM42_1235 | DM42_5472 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | 0.809 |
| DM42_1235 | WL94_02720 | DM42_1235 | DM42_5473 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 0.945 |
| DM42_1235 | WL94_35030 | DM42_1235 | DM42_1229 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 0.954 |
| DM42_1235 | aroB | DM42_1235 | DM42_1428 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) | 0.950 |
| DM42_1235 | aroC | DM42_1235 | DM42_240 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system | 0.583 |
| DM42_1235 | aroK | DM42_1235 | DM42_1429 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family | 0.837 |
| WI67_30635 | DM42_1235 | DM42_5472 | DM42_1235 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | 0.809 |
| WI67_30635 | WL94_02720 | DM42_5472 | DM42_5473 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 0.991 |
| WI67_30635 | WL94_35030 | DM42_5472 | DM42_1229 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 0.940 |
| WI67_30635 | aroB | DM42_5472 | DM42_1428 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) | 0.952 |
| WI67_30635 | aroC | DM42_5472 | DM42_240 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system | 0.583 |
| WI67_30635 | aroK | DM42_5472 | DM42_1429 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family | 0.825 |
| WL94_02720 | DM42_1235 | DM42_5473 | DM42_1235 | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | 0.945 |
| WL94_02720 | WI67_30635 | DM42_5473 | DM42_5472 | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate; Belongs to the type-II 3-dehydroquinase family | 0.991 |
| WL94_02720 | WL94_35030 | DM42_5473 | DM42_1229 | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 0.832 |
| WL94_02720 | aroA | DM42_5473 | DM42_782 | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate | 0.873 |
| WL94_02720 | aroB | DM42_5473 | DM42_1428 | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) | 0.807 |
| WL94_02720 | aroC | DM42_5473 | DM42_240 | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system | 0.600 |
| WL94_02720 | aroK | DM42_5473 | DM42_1429 | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family | 0.992 |
| WL94_02720 | mpl | DM42_5473 | DM42_1232 | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) | UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate; Belongs to the MurCDEF family. Mpl subfamily | 0.520 |
