yacG protein (Burkholderia cepacia) - STRING interaction network

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yacG

DNA gyrase inhibitor YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (66 aa)

Predicted Functional Partners:

zapD

0.871

coaE

0.754

gyrA

0.704

gyrB

0.687

outO

0.676

DM42_1263

0.626

parC

0.603

parE

0.582

WL94_35195

0.481

WL94_15265

0.432

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_1263	WL94_15265	DM42_1263	DM42_2426	annotation not available	General secretion pathway protein GspH; IV_pilin_GFxxxE- prepilin-type N-terminal cleavage/methylation domain protein	0.558
DM42_1263	WL94_35195	DM42_1263	DM42_1262	annotation not available	annotation not available	0.987
DM42_1263	coaE	DM42_1263	DM42_1265	annotation not available	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family	0.796
DM42_1263	outO	DM42_1263	DM42_1264	annotation not available	Type 4 prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	0.981
DM42_1263	yacG	DM42_1263	DM42_1267	annotation not available	DNA gyrase inhibitor YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	0.626
DM42_1263	zapD	DM42_1263	DM42_1266	annotation not available	Cell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	0.654
WL94_15265	DM42_1263	DM42_2426	DM42_1263	General secretion pathway protein GspH; IV_pilin_GFxxxE- prepilin-type N-terminal cleavage/methylation domain protein	annotation not available	0.558
WL94_15265	WL94_35195	DM42_2426	DM42_1262	General secretion pathway protein GspH; IV_pilin_GFxxxE- prepilin-type N-terminal cleavage/methylation domain protein	annotation not available	0.481
WL94_15265	outO	DM42_2426	DM42_1264	General secretion pathway protein GspH; IV_pilin_GFxxxE- prepilin-type N-terminal cleavage/methylation domain protein	Type 4 prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	0.524
WL94_15265	yacG	DM42_2426	DM42_1267	General secretion pathway protein GspH; IV_pilin_GFxxxE- prepilin-type N-terminal cleavage/methylation domain protein	DNA gyrase inhibitor YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	0.432
WL94_35195	DM42_1263	DM42_1262	DM42_1263	annotation not available	annotation not available	0.987
WL94_35195	WL94_15265	DM42_1262	DM42_2426	annotation not available	General secretion pathway protein GspH; IV_pilin_GFxxxE- prepilin-type N-terminal cleavage/methylation domain protein	0.481
WL94_35195	coaE	DM42_1262	DM42_1265	annotation not available	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family	0.745
WL94_35195	outO	DM42_1262	DM42_1264	annotation not available	Type 4 prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	0.956
WL94_35195	yacG	DM42_1262	DM42_1267	annotation not available	DNA gyrase inhibitor YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	0.481
WL94_35195	zapD	DM42_1262	DM42_1266	annotation not available	Cell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	0.530
coaE	DM42_1263	DM42_1265	DM42_1263	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family	annotation not available	0.796
coaE	WL94_35195	DM42_1265	DM42_1262	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family	annotation not available	0.745
coaE	outO	DM42_1265	DM42_1264	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family	Type 4 prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	0.905
coaE	yacG	DM42_1265	DM42_1267	Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family	DNA gyrase inhibitor YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	0.754

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