node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DM42_1331 | hemA | DM42_1331 | DM42_1332 | annotation not available | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | 0.762 |
DM42_1331 | prfA | DM42_1331 | DM42_1333 | annotation not available | Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA | 0.550 |
DM42_1331 | prmC | DM42_1331 | DM42_1334 | annotation not available | Protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif | 0.530 |
DM42_5204 | hemA | DM42_5204 | DM42_1332 | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | 0.952 |
DM42_5204 | hemB | DM42_5204 | DM42_1443 | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family | 0.950 |
DM42_5204 | hemC | DM42_5204 | DM42_2648 | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps | 0.510 |
DM42_5204 | hemDX | DM42_5204 | DM42_2649 | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | annotation not available | 0.781 |
DM42_5204 | hemE | DM42_5204 | DM42_1671 | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III | 0.409 |
DM42_5204 | hemL | DM42_5204 | DM42_880 | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | hemL: glutamate-1-semialdehyde-2,1-aminomutase | 0.829 |
gltX | hemA | DM42_3036 | DM42_1332 | Glutamyl-trna synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | 0.930 |
gltX | prfA | DM42_3036 | DM42_1333 | Glutamyl-trna synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) | Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA | 0.736 |
hemA | DM42_1331 | DM42_1332 | DM42_1331 | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | annotation not available | 0.762 |
hemA | DM42_5204 | DM42_1332 | DM42_5204 | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | 0.952 |
hemA | gltX | DM42_1332 | DM42_3036 | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | Glutamyl-trna synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) | 0.930 |
hemA | hemB | DM42_1332 | DM42_1443 | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family | 0.935 |
hemA | hemC | DM42_1332 | DM42_2648 | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps | 0.980 |
hemA | hemDX | DM42_1332 | DM42_2649 | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | annotation not available | 0.860 |
hemA | hemE | DM42_1332 | DM42_1671 | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III | 0.813 |
hemA | hemL | DM42_1332 | DM42_880 | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | hemL: glutamate-1-semialdehyde-2,1-aminomutase | 0.986 |
hemA | prfA | DM42_1332 | DM42_1333 | Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA) | Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA | 0.867 |