node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
mfd | nusA | DM42_3153 | DM42_200 | Transcription-repair coupling factor (superfamily ii helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | 0.445 |
mfd | nusG | DM42_3153 | DM42_1486 | Transcription-repair coupling factor (superfamily ii helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site | Transcription termination/antitermination protein nusg; Participates in transcription elongation, termination and antitermination | 0.758 |
mfd | rpoA | DM42_3153 | DM42_1447 | Transcription-repair coupling factor (superfamily ii helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site | Dna-directed rna polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates | 0.724 |
mfd | rpoB | DM42_3153 | DM42_1481 | Transcription-repair coupling factor (superfamily ii helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site | Dna-directed rna polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates | 0.995 |
mfd | rpoC | DM42_3153 | DM42_1480 | Transcription-repair coupling factor (superfamily ii helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site | Dna-directed rna polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates | 0.505 |
mfd | rpoZ | DM42_3153 | DM42_836 | Transcription-repair coupling factor (superfamily ii helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site | Dna-directed rna polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits | 0.578 |
nusA | mfd | DM42_200 | DM42_3153 | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | Transcription-repair coupling factor (superfamily ii helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site | 0.445 |
nusA | nusG | DM42_200 | DM42_1486 | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | Transcription termination/antitermination protein nusg; Participates in transcription elongation, termination and antitermination | 0.926 |
nusA | rplB | DM42_200 | DM42_1470 | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | Large subunit ribosomal protein l2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome | 0.703 |
nusA | rplJ | DM42_200 | DM42_1483 | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | Large subunit ribosomal protein l10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors | 0.559 |
nusA | rplL | DM42_200 | DM42_1482 | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | Large subunit ribosomal protein l7/l12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation | 0.803 |
nusA | rpoA | DM42_200 | DM42_1447 | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | Dna-directed rna polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates | 0.998 |
nusA | rpoB | DM42_200 | DM42_1481 | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | Dna-directed rna polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates | 0.998 |
nusA | rpoC | DM42_200 | DM42_1480 | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | Dna-directed rna polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates | 0.994 |
nusA | rpoZ | DM42_200 | DM42_836 | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | Dna-directed rna polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits | 0.979 |
nusA | rpsC | DM42_200 | DM42_1467 | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | Small subunit ribosomal protein s3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation | 0.796 |
nusG | mfd | DM42_1486 | DM42_3153 | Transcription termination/antitermination protein nusg; Participates in transcription elongation, termination and antitermination | Transcription-repair coupling factor (superfamily ii helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site | 0.758 |
nusG | nusA | DM42_1486 | DM42_200 | Transcription termination/antitermination protein nusg; Participates in transcription elongation, termination and antitermination | Transcription termination/antitermination protein nusa; Participates in both transcription termination and antitermination | 0.926 |
nusG | rplB | DM42_1486 | DM42_1470 | Transcription termination/antitermination protein nusg; Participates in transcription elongation, termination and antitermination | Large subunit ribosomal protein l2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome | 0.885 |
nusG | rplJ | DM42_1486 | DM42_1483 | Transcription termination/antitermination protein nusg; Participates in transcription elongation, termination and antitermination | Large subunit ribosomal protein l10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors | 0.951 |