STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macB_3annotation not available (232 aa)    
Predicted Functional Partners:
macA
Membrane fusion protein, macrolide-specific efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
  
 0.984
DM42_1525
Efflux transporter, rnd family, mfp subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
 
 0.982
DM42_1528
annotation not available
 
 
 0.977
DM42_1527
annotation not available
 
 
 0.975
DM42_3772
annotation not available
  
 0.859
DM42_3786
type_I_sec_TolC: type I secretion outer membrane , TolC family protein
  
 0.859
DM42_6055
Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
 
 0.668
DM42_4606
Membrane fusion protein, gold/copper resistance efflux system; RND_mfp: efflux transporter, RND family, MFP subunit
 
 0.665
DM42_4854
RND_mfp: efflux transporter, RND family, MFP subunit
 
 0.663
ftsY
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components
 
  
 0.655
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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