| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| WI67_09555 | WI67_25035 | DM42_3309 | DM42_6340 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex | 0.550 |
| WI67_09555 | era | DM42_3309 | DM42_691 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism | 0.565 |
| WI67_09555 | frr | DM42_3309 | DM42_3082 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another | 0.570 |
| WI67_09555 | gidB | DM42_3309 | DM42_1686 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil | Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA | 0.550 |
| WI67_09555 | rplR | DM42_3309 | DM42_1457 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance | 0.752 |
| WI67_09555 | rplS | DM42_3309 | DM42_755 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site | 0.643 |
| WI67_09555 | rsmH | DM42_3309 | DM42_1288 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil | Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA | 0.803 |
| WI67_09555 | rsmI | DM42_3309 | DM42_1540 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil | Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2’-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA | 0.687 |
| WI67_09555 | secA | DM42_3309 | DM42_1271 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil | Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family | 0.435 |
| WI67_25035 | WI67_09555 | DM42_6340 | DM42_3309 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil | 0.550 |
| WI67_25035 | frr | DM42_6340 | DM42_3082 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another | 0.770 |
| WI67_25035 | rplR | DM42_6340 | DM42_1457 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance | 0.924 |
| WI67_25035 | rplS | DM42_6340 | DM42_755 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site | 0.781 |
| WI67_25035 | rsmH | DM42_6340 | DM42_1288 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex | Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA | 0.462 |
| WI67_25035 | rsmI | DM42_6340 | DM42_1540 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex | Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2’-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA | 0.684 |
| WI67_25035 | secA | DM42_6340 | DM42_1271 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex | Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family | 0.761 |
| WL94_03000 | rsmI | DM42_1539 | DM42_1540 | UPF0102 protein WL94_03000; Belongs to the UPF0102 family | Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2’-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA | 0.787 |
| era | WI67_09555 | DM42_691 | DM42_3309 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil | 0.565 |
| era | frr | DM42_691 | DM42_3082 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another | 0.810 |
| era | gidB | DM42_691 | DM42_1686 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism | Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA | 0.710 |
