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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlpAEndolytic peptidoglycan transglycosylase RlpA; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides (203 aa)    
Predicted Functional Partners:
dksA
RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
      
 0.636
mrdB
Peptidoglycan glycosyltransferase MrdB; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily
  
  
 0.545
argA
N-Ac-Glu-synth: amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily
     
 0.502
WL94_31175
PBP_1a_fam: penicillin-binding , 1A family protein
 
     0.492
mrdA
Peptidoglycan D,D-transpeptidase MrdA; Catalyzes cross-linking of the peptidoglycan cell wall; Belongs to the transpeptidase family. MrdA subfamily
  
  
 0.487
dnaK
Chaperone protein DnaK; Acts as a chaperone
      
 0.475
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring; Belongs to the FtsA/MreB family
  
 
 0.474
WL94_25830
PBP_1a_fam: penicillin-binding , 1A family protein
 
  
 0.473
WI67_06445
annotation not available
 
  
 0.472
WL94_15740
PBP_1a_fam: penicillin-binding , 1A family protein
 
     0.469
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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