STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliARna polymerase sigma factor, flia/whig family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes (243 aa)    
Predicted Functional Partners:
flgM
Negative regulator of flagellin synthesis flgm; flgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM
  
 0.999
flgK
flgK_ends: flagellar hook-associated protein FlgK
 
  
 0.999
flhA
Flagellar biosynthesis protein flha; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
 
  
 0.984
flhB
Flagellar biosynthetic protein flhb; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
 
  
 0.984
flgC
Flagellar basal-body rod protein flgc; Belongs to the flagella basal body rod proteins family
 
 
 0.983
flgB
Flagellar basal-body rod protein flgb; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
 
 
 0.982
DM42_1587
Hypothetical protein; Bacterial flagellin C-terminal helical region family protein
  
 0.979
fliM
fliM_switch: flagellar motor switch protein FliM
 
 
 0.979
flgD
Flagellar basal-body rod modification protein flgd; Required for flagellar hook formation. May act as a scaffolding protein
 
  
 0.973
fliG
fliG: flagellar motor switch protein FliG
 
  
 0.972
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.