STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrdBRod shape determining protein roda; Peptidoglycan polymerase that is essential for cell wall elongation (382 aa)    
Predicted Functional Partners:
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall
 
 0.998
mreC
mreC: rod shape-determining protein MreC
 
 
 0.974
mreB_2
Rod shape-determining protein mreb and related proteins; mreB: cell shape determining , MreB/Mrl family protein
 
 0.913
DM42_2178
Serine-type d-ala-d-ala carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family
 
 
 0.848
mreB_1
Rod shape-determining protein mreb and related proteins; mreB: cell shape determining , MreB/Mrl family protein
 
 0.847
murG
Udp-n-acetylglucosamine--n-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol n-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
 
 0.838
mreD
shape_MreD: rod shape-determining protein MreD
  
  
 0.827
ftsI
Cell division protein ftsi (penicillin-binding protein 3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum
 
 0.820
murF
Udp-n-acetylmuramoyl-tripeptide--d-alanyl-d- alanine ligase family protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
 
 0.813
DM42_3725
Cell division protein ftsi (penicillin-binding protein 3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum
 
 0.797
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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