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aceK protein (Burkholderia cepacia) - STRING interaction network
"aceK" - Isocitrate dehydrogenase kinase/phosphatase in Burkholderia cepacia
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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aceKIsocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (605 aa)    
Predicted Functional Partners:
aceA
Isocit_lyase- isocitrate lyase (435 aa)
 
   
  0.813
icd
Prok_nadp_idh- isocitrate dehydrogenase, NADP-dependent (418 aa)
 
 
 
  0.802
WI67_15610
Carbonic anhydrase; Reversible hydration of carbon dioxide (255 aa)
              0.795
WL94_35510
annotation not available (527 aa)
   
   
  0.792
aceB
malate_syn_A- malate synthase A; Belongs to the malate synthase family (530 aa)
   
   
  0.734
fliE
fliE- flagellar hook-basal body complex protein FliE (114 aa)
           
  0.575
fliA
RNA polymerase sigma factor FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes (243 aa)
           
  0.575
katG
Catalase-peroxidase; Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (728 aa)
           
  0.575
metH
metH- methionine synthase (905 aa)
 
            0.574
WL94_30205
annotation not available (355 aa)
 
            0.572
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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