STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsbAProtein dithiol oxidoreductase (disulfide-forming); Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins. Involved in the production of protease and alkaline phosphatase, motility, metal resistance, and multi-drug resistance (212 aa)    
Predicted Functional Partners:
dsbB
Disulfide bond formation dsbb family protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity). Required for the production of extracellular protease
 
 
 0.960
DM42_2151
annotation not available
   
 0.922
DM42_2149
Belongs to the short-chain dehydrogenases/reductases (SDR) family
       0.862
lptD
Organic solvent tolerance family protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
 
   
 0.859
dsbD
annotation not available
 
 
 0.819
surA
Peptidyl-prolyl cis-trans isomerase sura; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
  
 
 0.782
DM42_1193
annotation not available
  
 
 
 0.740
apaH
Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
 
     0.727
DM42_1317
Thiol:disulfide interchange protein dsbc; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
  
 
 
 0.722
sspB
annotation not available
  
  
 0.709
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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