Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

WI67_14400

HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein (228 aa)

Predicted Functional Partners:

DM42_2385

0.569

WI67_04295

0.463

glmM

0.463

WI67_13955

0.434

WL94_32425

0.426

DM42_2386

0.417

WL94_16795

0.409

WI67_13950

0.408

WI67_13915

0.400

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

Export your current network:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_2385	DM42_2386	DM42_2385	DM42_2386	Oxidoreductase family, C-terminal alpha/beta domain protein	annotation not available	0.980
DM42_2385	WI67_14400	DM42_2385	DM42_2384	Oxidoreductase family, C-terminal alpha/beta domain protein	HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein	0.569
DM42_2386	DM42_2385	DM42_2386	DM42_2385	annotation not available	Oxidoreductase family, C-terminal alpha/beta domain protein	0.980
DM42_2386	WI67_14400	DM42_2386	DM42_2384	annotation not available	HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein	0.417
WI67_04295	WI67_14400	DM42_935	DM42_2384	annotation not available	HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein	0.463
WI67_04295	WL94_32425	DM42_935	DM42_2639	annotation not available	HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	0.463
WI67_13915	WI67_13950	DM42_2482	DM42_2476	annotation not available	annotation not available	0.504
WI67_13915	WI67_13955	DM42_2482	DM42_2475	annotation not available	annotation not available	0.555
WI67_13915	WI67_14400	DM42_2482	DM42_2384	annotation not available	HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein	0.400
WI67_13950	WI67_13915	DM42_2476	DM42_2482	annotation not available	annotation not available	0.504
WI67_13950	WI67_13955	DM42_2476	DM42_2475	annotation not available	annotation not available	0.998
WI67_13950	WI67_14400	DM42_2476	DM42_2384	annotation not available	HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein	0.408
WI67_13955	WI67_13915	DM42_2475	DM42_2482	annotation not available	annotation not available	0.555
WI67_13955	WI67_13950	DM42_2475	DM42_2476	annotation not available	annotation not available	0.998
WI67_13955	WI67_14400	DM42_2475	DM42_2384	annotation not available	HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein	0.434
WI67_14400	DM42_2385	DM42_2384	DM42_2385	HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein	Oxidoreductase family, C-terminal alpha/beta domain protein	0.569
WI67_14400	DM42_2386	DM42_2384	DM42_2386	HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein	annotation not available	0.417
WI67_14400	WI67_04295	DM42_2384	DM42_935	HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein	annotation not available	0.463
WI67_14400	WI67_13915	DM42_2384	DM42_2482	HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein	annotation not available	0.400
WI67_14400	WI67_13950	DM42_2384	DM42_2476	HAD-SF-IA-v1- HAD hydrolase, IA, variant 1 family protein	annotation not available	0.408

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