node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
WI67_12270 | WI67_22900 | DM42_2802 | DM42_3831 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 0.971 |
WI67_12270 | WL94_04345 | DM42_2802 | DM42_2606 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 0.978 |
WI67_12270 | WL94_10250 | DM42_2802 | DM42_4969 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily | 0.816 |
WI67_12270 | WL94_13975 | DM42_2802 | DM42_2257 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily | 0.816 |
WI67_12270 | ilvE | DM42_2802 | DM42_2438 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family | 0.960 |
WI67_22900 | WI67_12270 | DM42_3831 | DM42_2802 | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | 0.971 |
WI67_22900 | WL94_01645 | DM42_3831 | DM42_4670 | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family | 0.914 |
WI67_22900 | WL94_04345 | DM42_3831 | DM42_2606 | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 0.809 |
WI67_22900 | WL94_10250 | DM42_3831 | DM42_4969 | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily | 0.970 |
WI67_22900 | WL94_13975 | DM42_3831 | DM42_2257 | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily | 0.970 |
WI67_22900 | WL94_21715 | DM42_3831 | DM42_1083 | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family | 0.914 |
WI67_22900 | ilvE | DM42_3831 | DM42_2438 | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family | 0.950 |
WL94_01645 | WI67_22900 | DM42_4670 | DM42_3831 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 0.914 |
WL94_01645 | WL94_04345 | DM42_4670 | DM42_2606 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 0.914 |
WL94_01645 | WL94_21715 | DM42_4670 | DM42_1083 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family | 0.819 |
WL94_01645 | ilvE | DM42_4670 | DM42_2438 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family | 0.917 |
WL94_04345 | WI67_12270 | DM42_2606 | DM42_2802 | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | 0.978 |
WL94_04345 | WI67_22900 | DM42_2606 | DM42_3831 | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 0.809 |
WL94_04345 | WL94_01645 | DM42_2606 | DM42_4670 | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family | 0.914 |
WL94_04345 | WL94_10250 | DM42_2606 | DM42_4969 | ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily | 0.964 |