Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Fusion
Genes that are sometimes fused into single open reading frames.
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Databases
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Coexpression
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WL94_08880
annotation not available (169 aa)
Predicted Functional Partners:
prnD
annotation not available
0.573
ppk1
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1
node2
node1 accession
node2 accession
node1 annotation
node2 annotation
score
WL94_08880
WL94_08885
DM42_2493
DM42_2495
annotation not available
annotation not available
0.424
WL94_08880
WL94_08890
DM42_2493
DM42_2496
annotation not available
annotation not available
0.424
WL94_08880
ppk1
DM42_2493
DM42_414
annotation not available
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family
0.473
WL94_08880
prnD
DM42_2493
DM42_7276
annotation not available
annotation not available
0.573
WL94_08885
WL94_08880
DM42_2495
DM42_2493
annotation not available
annotation not available
0.424
WL94_08885
WL94_08890
DM42_2495
DM42_2496
annotation not available
annotation not available
0.969
WL94_08890
WL94_08880
DM42_2496
DM42_2493
annotation not available
annotation not available
0.424
WL94_08890
WL94_08885
DM42_2496
DM42_2495
annotation not available
annotation not available
0.969
ppk1
WL94_08880
DM42_414
DM42_2493
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family
annotation not available
0.473
prnD
WL94_08880
DM42_7276
DM42_2493
annotation not available
annotation not available
0.573
Network Stats
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Functional enrichments in your networkNote: some enrichments may be expected here (why?) explain columns
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: