Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurence

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[Homology]

Score

WI67_13840

annotation not available (285 aa)

Predicted Functional Partners:

pdxH

0.682

WL94_08935

0.586

sufS

0.514

DM42_2977

0.510

WI67_02435

0.467

WL94_08905

0.407

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

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same PNG format, but resolution at 400 dpi

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_2977	WI67_13840	DM42_2977	DM42_2501	comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2	annotation not available	0.510
WI67_02435	WI67_13840	DM42_1305	DM42_2501	annotation not available	annotation not available	0.467
WI67_02435	WL94_08935	DM42_1305	DM42_2505	annotation not available	annotation not available	0.572
WI67_13840	DM42_2977	DM42_2501	DM42_2977	annotation not available	comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2	0.510
WI67_13840	WI67_02435	DM42_2501	DM42_1305	annotation not available	annotation not available	0.467
WI67_13840	WL94_08905	DM42_2501	DM42_2499	annotation not available	annotation not available	0.407
WI67_13840	WL94_08935	DM42_2501	DM42_2505	annotation not available	annotation not available	0.586
WI67_13840	pdxH	DM42_2501	DM42_2500	annotation not available	Pyridoxine/pyridoxamine 5’-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5’- phosphate (PNP) or pyridoxamine 5’-phosphate (PMP) into pyridoxal 5’-phosphate (PLP)	0.682
WI67_13840	sufS	DM42_2501	DM42_4548	annotation not available	sufS- cysteine desulfurase, SufS family protein; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	0.514
WL94_08905	WI67_13840	DM42_2499	DM42_2501	annotation not available	annotation not available	0.407
WL94_08905	pdxH	DM42_2499	DM42_2500	annotation not available	Pyridoxine/pyridoxamine 5’-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5’- phosphate (PNP) or pyridoxamine 5’-phosphate (PMP) into pyridoxal 5’-phosphate (PLP)	0.574
WL94_08935	WI67_02435	DM42_2505	DM42_1305	annotation not available	annotation not available	0.572
WL94_08935	WI67_13840	DM42_2505	DM42_2501	annotation not available	annotation not available	0.586
pdxH	WI67_13840	DM42_2500	DM42_2501	Pyridoxine/pyridoxamine 5’-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5’- phosphate (PNP) or pyridoxamine 5’-phosphate (PMP) into pyridoxal 5’-phosphate (PLP)	annotation not available	0.682
pdxH	WL94_08905	DM42_2500	DM42_2499	Pyridoxine/pyridoxamine 5’-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5’- phosphate (PNP) or pyridoxamine 5’-phosphate (PMP) into pyridoxal 5’-phosphate (PLP)	annotation not available	0.574
sufS	WI67_13840	DM42_4548	DM42_2501	sufS- cysteine desulfurase, SufS family protein; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	annotation not available	0.514

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