node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DM42_2977 | WI67_13815 | DM42_2977 | DM42_2506 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | 0.617 |
DM42_2977 | mutL | DM42_2977 | DM42_1072 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex | 0.713 |
DM42_2977 | nnrD | DM42_2977 | DM42_3184 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family | 0.579 |
DM42_2977 | polA | DM42_2977 | DM42_4183 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.802 |
DM42_2977 | recJ | DM42_2977 | DM42_2972 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | recJ: single-stranded-DNA-specific exonuclease RecJ | 0.829 |
DM42_2977 | yeaZ | DM42_2977 | DM42_3054 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaB; T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ | 0.603 |
WI67_13815 | DM42_2977 | DM42_2506 | DM42_2977 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | 0.617 |
WI67_13815 | WL94_08935 | DM42_2506 | DM42_2505 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | annotation not available | 0.920 |
WI67_13815 | mutL | DM42_2506 | DM42_1072 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex | 0.850 |
WI67_13815 | nnrD | DM42_2506 | DM42_3184 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family | 0.880 |
WI67_13815 | polA | DM42_2506 | DM42_4183 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.666 |
WI67_13815 | queG | DM42_2506 | DM42_2507 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family | 0.800 |
WI67_13815 | recJ | DM42_2506 | DM42_2972 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | recJ: single-stranded-DNA-specific exonuclease RecJ | 0.624 |
WI67_13815 | tsaD | DM42_2506 | DM42_4174 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family | 0.843 |
WI67_13815 | xerD | DM42_2506 | DM42_2509 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | recomb_XerD: tyrosine recombinase XerD | 0.681 |
WI67_13815 | yeaZ | DM42_2506 | DM42_3054 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | tRNA threonylcarbamoyladenosine biosynthesis protein TsaB; T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ | 0.898 |
WL94_08935 | WI67_13815 | DM42_2505 | DM42_2506 | annotation not available | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE | 0.920 |
WL94_08935 | mutL | DM42_2505 | DM42_1072 | annotation not available | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex | 0.539 |
WL94_08935 | nnrD | DM42_2505 | DM42_3184 | annotation not available | Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family | 0.655 |
WL94_08935 | queG | DM42_2505 | DM42_2507 | annotation not available | Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family | 0.755 |