node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
WI67_14905 | WI67_14910 | DM42_2284 | DM42_2283 | kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily | yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein | 0.998 |
WI67_14905 | WL94_20930 | DM42_2284 | DM42_932 | kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily | annotation not available | 0.907 |
WI67_14905 | WL94_21540 | DM42_2284 | DM42_1046 | kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily | UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family | 0.825 |
WI67_14905 | kdsA | DM42_2284 | DM42_2980 | kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily | 2-dehydro-3-deoxyphosphooctonate aldolase; KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family | 0.998 |
WI67_14905 | kdsB | DM42_2284 | DM42_2521 | kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | 0.950 |
WI67_14905 | lpxA | DM42_2284 | DM42_3091 | kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell | 0.897 |
WI67_14905 | lpxB | DM42_2284 | DM42_3092 | kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell | 0.922 |
WI67_14905 | lpxC | DM42_2284 | DM42_1273 | kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily | UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family | 0.852 |
WI67_14905 | lpxD | DM42_2284 | DM42_3089 | kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily | UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily | 0.902 |
WI67_14905 | lpxK | DM42_2284 | DM42_2523 | kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) | 0.927 |
WI67_14910 | WI67_14905 | DM42_2283 | DM42_2284 | yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein | kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily | 0.998 |
WI67_14910 | WL94_20930 | DM42_2283 | DM42_932 | yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein | annotation not available | 0.657 |
WI67_14910 | WL94_21540 | DM42_2283 | DM42_1046 | yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein | UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family | 0.484 |
WI67_14910 | kdsA | DM42_2283 | DM42_2980 | yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein | 2-dehydro-3-deoxyphosphooctonate aldolase; KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family | 0.996 |
WI67_14910 | kdsB | DM42_2283 | DM42_2521 | yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | 0.993 |
WI67_14910 | lpxA | DM42_2283 | DM42_3091 | yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell | 0.703 |
WI67_14910 | lpxB | DM42_2283 | DM42_3092 | yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell | 0.680 |
WI67_14910 | lpxC | DM42_2283 | DM42_1273 | yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein | UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family | 0.662 |
WI67_14910 | lpxD | DM42_2283 | DM42_3089 | yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein | UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily | 0.785 |
WI67_14910 | lpxK | DM42_2283 | DM42_2523 | yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) | 0.642 |