node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DM42_2522 | DM42_2977 | DM42_2522 | DM42_2977 | UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | 0.524 |
DM42_2522 | adk | DM42_2522 | DM42_2520 | UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family | 0.616 |
DM42_2522 | kdsB | DM42_2522 | DM42_2521 | UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | 0.758 |
DM42_2522 | lpxK | DM42_2522 | DM42_2523 | UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) | 0.915 |
DM42_2522 | metG | DM42_2522 | DM42_2632 | UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily | 0.455 |
DM42_2522 | nnrD | DM42_2522 | DM42_3184 | UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family | Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family | 0.524 |
DM42_2522 | pheT | DM42_2522 | DM42_220 | UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family | pheT_bact: phenylalanine--tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily | 0.504 |
DM42_2977 | DM42_2522 | DM42_2977 | DM42_2522 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family | 0.524 |
DM42_2977 | kdsB | DM42_2977 | DM42_2521 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | 0.524 |
DM42_2977 | lpxK | DM42_2977 | DM42_2523 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) | 0.831 |
DM42_2977 | nnrD | DM42_2977 | DM42_3184 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family | 0.579 |
adk | DM42_2522 | DM42_2520 | DM42_2522 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family | UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family | 0.616 |
adk | kdsB | DM42_2520 | DM42_2521 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | 0.653 |
adk | lpxK | DM42_2520 | DM42_2523 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) | 0.564 |
adk | metG | DM42_2520 | DM42_2632 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily | 0.532 |
adk | nnrD | DM42_2520 | DM42_3184 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family | Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family | 0.466 |
adk | pheT | DM42_2520 | DM42_220 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family | pheT_bact: phenylalanine--tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily | 0.481 |
kdsB | DM42_2522 | DM42_2521 | DM42_2522 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family | 0.758 |
kdsB | DM42_2977 | DM42_2521 | DM42_2977 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 | 0.524 |
kdsB | adk | DM42_2521 | DM42_2520 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family | 0.653 |