DM42_2522 protein (Burkholderia cepacia) - STRING interaction network

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DM42_2522

UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family (64 aa)

Predicted Functional Partners:

lpxK

0.915

kdsB

0.758

adk

0.616

nnrD

0.524

DM42_2977

0.524

pheT

0.504

metG

0.455

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_2522	DM42_2977	DM42_2522	DM42_2977	UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family	comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2	0.524
DM42_2522	adk	DM42_2522	DM42_2520	UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	0.616
DM42_2522	kdsB	DM42_2522	DM42_2521	UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family	3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	0.758
DM42_2522	lpxK	DM42_2522	DM42_2523	UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family	Tetraacyldisaccharide 4’-kinase; Transfers the gamma-phosphate of ATP to the 4’-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4’-bis-phosphate (lipid IVA)	0.915
DM42_2522	metG	DM42_2522	DM42_2632	UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family	Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily	0.455
DM42_2522	nnrD	DM42_2522	DM42_3184	UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.524
DM42_2522	pheT	DM42_2522	DM42_220	UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family	pheT_bact- phenylalanine--tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	0.504
DM42_2977	DM42_2522	DM42_2977	DM42_2522	comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2	UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family	0.524
DM42_2977	kdsB	DM42_2977	DM42_2521	comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2	3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	0.524
DM42_2977	lpxK	DM42_2977	DM42_2523	comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2	Tetraacyldisaccharide 4’-kinase; Transfers the gamma-phosphate of ATP to the 4’-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4’-bis-phosphate (lipid IVA)	0.831
DM42_2977	nnrD	DM42_2977	DM42_3184	comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.579
adk	DM42_2522	DM42_2520	DM42_2522	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family	0.616
adk	kdsB	DM42_2520	DM42_2521	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	0.653
adk	lpxK	DM42_2520	DM42_2523	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	Tetraacyldisaccharide 4’-kinase; Transfers the gamma-phosphate of ATP to the 4’-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4’-bis-phosphate (lipid IVA)	0.564
adk	metG	DM42_2520	DM42_2632	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily	0.532
adk	nnrD	DM42_2520	DM42_3184	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.466
adk	pheT	DM42_2520	DM42_220	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	pheT_bact- phenylalanine--tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	0.481
kdsB	DM42_2522	DM42_2521	DM42_2522	3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	UPF0434 protein CEQ23_15940; Belongs to the UPF0434 family	0.758
kdsB	DM42_2977	DM42_2521	DM42_2977	3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2	0.524
kdsB	adk	DM42_2521	DM42_2520	3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	0.653

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