STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_2525Iron/manganese superoxide dismutase, alpha-hairpin domain protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (192 aa)    
Predicted Functional Partners:
DM42_1766
Catalase family protein; Has an organic peroxide-dependent peroxidase activity
  
 0.946
katG
Catalase/peroxidase hpi; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity
     
 0.926
rpsI
Small subunit ribosomal protein s9; Belongs to the universal ribosomal protein uS9 family
  
 0.903
rpsF
Small subunit ribosomal protein s6; Binds together with S18 to 16S ribosomal RNA
   
 0.897
rpsP
Small subunit ribosomal protein s16; Belongs to the bacterial ribosomal protein bS16 family
   
 0.878
rpsE
Small subunit ribosomal protein s5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
   
 0.877
rpsG
Small subunit ribosomal protein s7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
   
 0.856
rpsO
Small subunit ribosomal protein s15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
   
  0.849
rpsJ
Small subunit ribosomal protein s10; Involved in the binding of tRNA to the ribosomes
   
 0.846
rpsD
Small subunit ribosomal protein s4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
  
 0.842
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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