STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WL94_04035Monomer_idh: isocitrate dehydrogenase, NADP-dependent (742 aa)    
Predicted Functional Partners:
acnB
acnB: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family
 
 
 0.942
icd
Prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent
  
 
 0.940
acnA
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
   
 0.935
sucA
2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component
   
 
 0.923
purB
purB: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
  
  0.835
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate
  
  
 0.832
WL94_31655
annotation not available
  
 
  0.831
WI67_03110
annotation not available
     
 0.822
aspA
Class II fumarate hydratase; aspA: aspartate ammonia-lyase
   
 
 0.817
gltD
annotation not available
   
 
 0.812
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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