STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_2544Isocitrate dehydrogenase, nadp-dependent; Belongs to the monomeric-type IDH family (742 aa)    
Predicted Functional Partners:
acnB
Aconitate hydratase 2 / 2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family
 
 
 0.951
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate
   
 0.939
icd
Prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent
  
 
 0.935
sucA
2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component
   
 
 0.923
DM42_4292
Hypothetical protein; Aconitase subunit 1
     
  0.900
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate
  
  
 0.868
DM42_1419
annotation not available
    
 0.840
purB
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
  
 
  0.829
DM42_3245
annotation not available
  
  
  0.827
gltD
annotation not available
     
 0.818
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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