node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DM42_5920 | nadA | DM42_5920 | DM42_2561 | Bifunctional nmn adenylyltransferase/nudix hydrolase; Belongs to the Nudix hydrolase family | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | 0.666 |
DM42_5920 | nadB | DM42_5920 | DM42_2563 | Bifunctional nmn adenylyltransferase/nudix hydrolase; Belongs to the Nudix hydrolase family | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate | 0.653 |
DM42_5920 | nadC | DM42_5920 | DM42_2562 | Bifunctional nmn adenylyltransferase/nudix hydrolase; Belongs to the Nudix hydrolase family | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family | 0.963 |
DM42_5920 | nadD | DM42_5920 | DM42_2764 | Bifunctional nmn adenylyltransferase/nudix hydrolase; Belongs to the Nudix hydrolase family | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) | 0.929 |
DM42_5920 | nadE | DM42_5920 | DM42_2663 | Bifunctional nmn adenylyltransferase/nudix hydrolase; Belongs to the Nudix hydrolase family | Nad+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source | 0.982 |
DM42_5920 | pncB | DM42_5920 | DM42_725 | Bifunctional nmn adenylyltransferase/nudix hydrolase; Belongs to the Nudix hydrolase family | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP | 0.965 |
hrpA | nadA | DM42_2932 | DM42_2561 | DEAH_box_HrpA: ATP-dependent helicase HrpA | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | 0.669 |
hrpA | purL | DM42_2932 | DM42_3186 | DEAH_box_HrpA: ATP-dependent helicase HrpA | Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate | 0.480 |
nadA | DM42_5920 | DM42_2561 | DM42_5920 | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | Bifunctional nmn adenylyltransferase/nudix hydrolase; Belongs to the Nudix hydrolase family | 0.666 |
nadA | hrpA | DM42_2561 | DM42_2932 | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | DEAH_box_HrpA: ATP-dependent helicase HrpA | 0.669 |
nadA | nadB | DM42_2561 | DM42_2563 | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate | 0.998 |
nadA | nadC | DM42_2561 | DM42_2562 | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family | 0.998 |
nadA | nadD | DM42_2561 | DM42_2764 | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) | 0.640 |
nadA | nadE | DM42_2561 | DM42_2663 | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | Nad+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source | 0.759 |
nadA | nadX | DM42_2561 | DM42_6105 | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | Aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate | 0.923 |
nadA | nrdR | DM42_2561 | DM42_1022 | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | Transcriptional regulator nrdr; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes | 0.632 |
nadA | pncB | DM42_2561 | DM42_725 | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP | 0.637 |
nadA | purL | DM42_2561 | DM42_3186 | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate | 0.797 |
nadB | DM42_5920 | DM42_2563 | DM42_5920 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate | Bifunctional nmn adenylyltransferase/nudix hydrolase; Belongs to the Nudix hydrolase family | 0.653 |
nadB | nadA | DM42_2563 | DM42_2561 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate | Quinolinate synthetase complex, a subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate | 0.998 |