nadA protein (Burkholderia cepacia) - STRING interaction network

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nadA

Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily (378 aa)

Predicted Functional Partners:

nadC

0.998

nadB

0.998

nadX

0.937

polA

0.781

purL

0.771

WL94_32335

0.724

ribD

0.633

WL94_38975

0.615

hrpA

0.609

yidC

0.602

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WL94_32335	WL94_38975	DM42_2663	DM42_5920	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	annotation not available	0.977
WL94_32335	nadA	DM42_2663	DM42_2561	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily	0.724
WL94_32335	nadB	DM42_2663	DM42_2563	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate	0.680
WL94_32335	nadC	DM42_2663	DM42_2562	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadC- nicotinate-nucleotide diphosphorylase; Belongs to the NadC/ModD family	0.741
WL94_32335	purL	DM42_2663	DM42_3186	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	0.813
WL94_32335	ribD	DM42_2663	DM42_881	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.603
WL94_38975	WL94_32335	DM42_5920	DM42_2663	annotation not available	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	0.977
WL94_38975	nadA	DM42_5920	DM42_2561	annotation not available	Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily	0.615
WL94_38975	nadB	DM42_5920	DM42_2563	annotation not available	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate	0.577
WL94_38975	nadC	DM42_5920	DM42_2562	annotation not available	nadC- nicotinate-nucleotide diphosphorylase; Belongs to the NadC/ModD family	0.925
hrpA	nadA	DM42_2932	DM42_2561	DEAH_box_HrpA- ATP-dependent helicase HrpA	Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily	0.609
hrpA	polA	DM42_2932	DM42_4183	DEAH_box_HrpA- ATP-dependent helicase HrpA	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity	0.493
hrpA	purL	DM42_2932	DM42_3186	DEAH_box_HrpA- ATP-dependent helicase HrpA	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	0.479
hrpA	yidC	DM42_2932	DM42_1790	DEAH_box_HrpA- ATP-dependent helicase HrpA	Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	0.686
nadA	WL94_32335	DM42_2561	DM42_2663	Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	0.724
nadA	WL94_38975	DM42_2561	DM42_5920	Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily	annotation not available	0.615
nadA	hrpA	DM42_2561	DM42_2932	Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily	DEAH_box_HrpA- ATP-dependent helicase HrpA	0.609
nadA	nadB	DM42_2561	DM42_2563	Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate	0.998
nadA	nadC	DM42_2561	DM42_2562	Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily	nadC- nicotinate-nucleotide diphosphorylase; Belongs to the NadC/ModD family	0.998
nadA	nadX	DM42_2561	DM42_6105	Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily	Probable L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	0.937

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