Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

cysN

Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily (426 aa)

Predicted Functional Partners:

WL94_04295

0.999

DM42_1043

0.997

WI67_11810

0.997

cysH

0.982

WL94_19720

0.964

cysW

0.957

cysA

0.939

sbp

0.918

WI67_13360

0.889

WL94_28740

0.862

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_1043	WI67_11810	DM42_1043	DM42_2901	apsK- adenylylsulfate kinase	cysD- sulfate adenylyltransferase, small subunit	0.983
DM42_1043	WI67_13360	DM42_1043	DM42_2593	apsK- adenylylsulfate kinase	annotation not available	0.815
DM42_1043	WL94_04295	DM42_1043	DM42_2596	apsK- adenylylsulfate kinase	cysD- sulfate adenylyltransferase, small subunit	0.978
DM42_1043	WL94_19720	DM42_1043	DM42_2900	apsK- adenylylsulfate kinase	Multifunctional fusion protein; Catalyzes the synthesis of activated sulfate; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily	0.964
DM42_1043	WL94_28740	DM42_1043	DM42_96	apsK- adenylylsulfate kinase	3a0106s03- sulfate ABC transporter, sulfate-binding family protein	0.428
DM42_1043	cysA	DM42_1043	DM42_93	apsK- adenylylsulfate kinase	Sulfate/thiosulfate import ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family	0.699
DM42_1043	cysH	DM42_1043	DM42_2595	apsK- adenylylsulfate kinase	Thioredoxin-dependent 5’-adenylylsulfate reductase; Reduction of activated sulfate into sulfite. Uses adenylyl sulfate as substrate and thioredoxin as electron donor; Belongs to the PAPS reductase family. CysH subfamily	0.996
DM42_1043	cysN	DM42_1043	DM42_2597	apsK- adenylylsulfate kinase	Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily	0.997
DM42_1043	cysW	DM42_1043	DM42_94	apsK- adenylylsulfate kinase	permease_CysW- sulfate ABC transporter, permease protein CysW	0.714
DM42_1043	sbp	DM42_1043	DM42_2118	apsK- adenylylsulfate kinase	annotation not available	0.428
WI67_11810	DM42_1043	DM42_2901	DM42_1043	cysD- sulfate adenylyltransferase, small subunit	apsK- adenylylsulfate kinase	0.983
WI67_11810	WI67_13360	DM42_2901	DM42_2593	cysD- sulfate adenylyltransferase, small subunit	annotation not available	0.830
WI67_11810	WL94_04295	DM42_2901	DM42_2596	cysD- sulfate adenylyltransferase, small subunit	cysD- sulfate adenylyltransferase, small subunit	0.813
WI67_11810	WL94_19720	DM42_2901	DM42_2900	cysD- sulfate adenylyltransferase, small subunit	Multifunctional fusion protein; Catalyzes the synthesis of activated sulfate; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily	0.999
WI67_11810	WL94_28740	DM42_2901	DM42_96	cysD- sulfate adenylyltransferase, small subunit	3a0106s03- sulfate ABC transporter, sulfate-binding family protein	0.831
WI67_11810	cysA	DM42_2901	DM42_93	cysD- sulfate adenylyltransferase, small subunit	Sulfate/thiosulfate import ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family	0.926
WI67_11810	cysH	DM42_2901	DM42_2595	cysD- sulfate adenylyltransferase, small subunit	Thioredoxin-dependent 5’-adenylylsulfate reductase; Reduction of activated sulfate into sulfite. Uses adenylyl sulfate as substrate and thioredoxin as electron donor; Belongs to the PAPS reductase family. CysH subfamily	0.895
WI67_11810	cysN	DM42_2901	DM42_2597	cysD- sulfate adenylyltransferase, small subunit	Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily	0.997
WI67_11810	cysW	DM42_2901	DM42_94	cysD- sulfate adenylyltransferase, small subunit	permease_CysW- sulfate ABC transporter, permease protein CysW	0.918
WI67_11810	sbp	DM42_2901	DM42_2118	cysD- sulfate adenylyltransferase, small subunit	annotation not available	0.829

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