STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobJCobalt-precorrin 5a hydrolase / precorrin-3b c17-methyltransferase; Cobalamin biosynthesis protein CbiG; cobJ_cbiH: precorrin-3B C17-methyltransferase (571 aa)    
Predicted Functional Partners:
cobM
Precorrin-4/cobalt-precorrin-4 C11-methyltransferase; cobM_cbiF: precorrin-4 C11-methyltransferase
 0.999
cbiD
Cobalt-precorrin-5B (C1)-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
 
 0.999
cbiT
cbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit
 
  
 0.999
DM42_24
annotation not available
  
 0.999
cobI
Precorrin-2/cobalt-factor-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A
  
 0.999
cobG
cobG: precorrin-3B synthase
 
 0.996
cobQ
Adenosylcobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
  
 0.995
rplK
Large subunit ribosomal protein l11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
    
   0.994
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
  
 0.980
cbiA
Cobb/cobq-like glutamine amidotransferase domain protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
  
 0.970
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.