cobQ protein (Burkholderia cepacia) - STRING interaction network

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cobQ

Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (500 aa)

Predicted Functional Partners:

cobD

0.999

cobO

0.998

WI67_13220

0.997

WL94_04410

0.996

cobJ

0.995

cbiA

0.994

cbiT

0.974

WI67_05200

0.962

bluB

0.955

WI67_13245

0.946

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WI67_05200	WI67_13220	DM42_753	DM42_2621	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	0.945
WI67_05200	WI67_13245	DM42_753	DM42_2616	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5’-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5’-phosphate; Belongs to the CobS family	0.565
WI67_05200	WL94_04410	DM42_753	DM42_2619	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	L_thr_O3P_dcar- threonine-phosphate decarboxylase	0.868
WI67_05200	cbiA	DM42_753	DM42_45	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	0.600
WI67_05200	cbiT	DM42_753	DM42_22	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cbiT- precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit	0.867
WI67_05200	cobD	DM42_753	DM42_2620	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	0.829
WI67_05200	cobJ	DM42_753	DM42_26	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	Cobalamin biosynthesis protein CbiG; cobJ_cbiH- precorrin-3B C17-methyltransferase	0.900
WI67_05200	cobO	DM42_753	DM42_44	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	0.947
WI67_05200	cobQ	DM42_753	DM42_2622	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	0.962
WI67_13220	WI67_05200	DM42_2621	DM42_753	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	0.945
WI67_13220	WI67_13245	DM42_2621	DM42_2616	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5’-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5’-phosphate; Belongs to the CobS family	0.995
WI67_13220	WL94_04410	DM42_2621	DM42_2619	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	L_thr_O3P_dcar- threonine-phosphate decarboxylase	0.995
WI67_13220	bluB	DM42_2621	DM42_1005	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	bluB- 5,6-dimethylbenzimidazole synthase	0.790
WI67_13220	cbiA	DM42_2621	DM42_45	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family	0.933
WI67_13220	cbiT	DM42_2621	DM42_22	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	cbiT- precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit	0.934
WI67_13220	cobD	DM42_2621	DM42_2620	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	0.998
WI67_13220	cobJ	DM42_2621	DM42_26	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	Cobalamin biosynthesis protein CbiG; cobJ_cbiH- precorrin-3B C17-methyltransferase	0.949
WI67_13220	cobO	DM42_2621	DM42_44	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	0.992
WI67_13220	cobQ	DM42_2621	DM42_2622	Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family	Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	0.997
WI67_13245	WI67_05200	DM42_2616	DM42_753	Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5’-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5’-phosphate; Belongs to the CobS family	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	0.565

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