STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argHargH: argininosuccinate lyase (469 aa)    
Predicted Functional Partners:
argG
Belongs to the argininosuccinate synthase family. Type 2 subfamily
 
 
 0.996
argA
Belongs to the acetyltransferase family. ArgA subfamily.
 
  
 0.992
argJ
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
 
  
 0.980
argB
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate
 
  
 0.971
purB
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
  
 
 0.931
carB
Belongs to the CarB family
 
  
 0.917
DM42_5497
Belongs to the arginase family. ProRule:PRU00742, ECO:0000256|RuleBase:RU003684,
  
 
 0.917
aspA
Class II fumarate hydratase; aspA: aspartate ammonia-lyase
     
0.902
hisI
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
 
  
 0.894
argC_1
Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
 
  
 0.888
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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