STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
DM42_26913-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family (246 aa)    
Predicted Functional Partners:
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase fabz; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
 
 0.808
DM42_2689
annotation not available
 
   
 0.790
fabF
Beta-ketoacyl-acyl-carrier-protein synthase ii; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
 
 0.775
DM42_6948
3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl synthase, C-terminal domain protein
 
 0.773
fabH
3-oxoacyl-[acyl-carrier-] synthase III family protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids
  
 
 0.710
DM42_2304
3-oxoacyl-ACP synthase; Thiolase, N-terminal domain protein; Belongs to the beta-ketoacyl-ACP synthases family
  
 0.690
DM42_4935
annotation not available
  
 
 0.671
DM42_4936
annotation not available
  
 
 0.671
DM42_6952
3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Conserved hypothetical protein
     
  0.650
DM42_1047
annotation not available
  
 0.601
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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