Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein (111 aa)
Predicted Functional Partners:
Autotrans_barl- outer membrane autotransporter barrel domain protein (1767 aa)
Maf-like protein WL94_24445; Maf- septum formation protein Maf (215 aa)
RNaseEG- ribonuclease, Rne/Rng family domain protein (489 aa)
Conserved hypothetical protein (182 aa)
Conserved hypothetical protein (301 aa)
annotation not available (247 aa)
Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (147 aa)
spaO_YscQ- type III secretion apparatus protein, YscQ/HrcQ family (383 aa)
Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family (156 aa)