Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

WL94_39725

annotation not available (244 aa)

Predicted Functional Partners:

WI67_11955

0.988

DM42_2868

0.935

WI67_09145

0.897

WL94_34810

0.883

DM42_4529

0.863

tolR

0.856

WI67_09140

0.827

DM42_4531

0.763

WI67_24585

0.682

WI67_09155

0.667

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

Export your current network:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but resolution at 400 dpi

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_2868	DM42_4529	DM42_2868	DM42_4529	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.622
DM42_2868	WI67_09140	DM42_2868	DM42_3475	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.641
DM42_2868	WI67_09145	DM42_2868	DM42_3474	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.593
DM42_2868	WI67_11955	DM42_2868	DM42_2866	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.917
DM42_2868	WI67_24585	DM42_2868	DM42_3537	tonB_Cterm- TonB family C-terminal domain protein	Pal_lipo- peptidoglycan-associated lipoprotein; Belongs to the ompA family	0.405
DM42_2868	WL94_34810	DM42_2868	DM42_1190	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.669
DM42_2868	WL94_39725	DM42_2868	DM42_2867	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.935
DM42_2868	tolR	DM42_2868	DM42_1027	tonB_Cterm- TonB family C-terminal domain protein	tolR- protein TolR	0.593
DM42_4529	DM42_2868	DM42_4529	DM42_2868	annotation not available	tonB_Cterm- TonB family C-terminal domain protein	0.622
DM42_4529	DM42_4531	DM42_4529	DM42_4531	annotation not available	tonB_Cterm- TonB family C-terminal domain protein	0.945
DM42_4529	WI67_09155	DM42_4529	DM42_3472	annotation not available	Protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	0.594
DM42_4529	WI67_24585	DM42_4529	DM42_3537	annotation not available	Pal_lipo- peptidoglycan-associated lipoprotein; Belongs to the ompA family	0.636
DM42_4529	WL94_39725	DM42_4529	DM42_2867	annotation not available	annotation not available	0.863
DM42_4531	DM42_4529	DM42_4531	DM42_4529	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.945
DM42_4531	WI67_09140	DM42_4531	DM42_3475	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.695
DM42_4531	WI67_09145	DM42_4531	DM42_3474	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.717
DM42_4531	WI67_11955	DM42_4531	DM42_2866	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.842
DM42_4531	WI67_24585	DM42_4531	DM42_3537	tonB_Cterm- TonB family C-terminal domain protein	Pal_lipo- peptidoglycan-associated lipoprotein; Belongs to the ompA family	0.477
DM42_4531	WL94_34810	DM42_4531	DM42_1190	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.712
DM42_4531	WL94_39725	DM42_4531	DM42_2867	tonB_Cterm- TonB family C-terminal domain protein	annotation not available	0.763

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Coexpression

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