STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_2960Belongs to the low molecular weight phosphotyrosine protein phosphatase family (160 aa)    
Predicted Functional Partners:
ptp
Low molecular weight protein-tyrosine-phosphatase ptp; Belongs to the low molecular weight phosphotyrosine protein phosphatase family
  
  
 0.912
DM42_216
annotation not available
    
 0.829
DM42_4463
annotation not available
     
  0.800
iscR
Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; iscR: iron-sulfur cluster assembly transcription factor IscR
       0.706
iscS_2
Cysteine desulfurase iscs; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
       0.586
DM42_3756
annotation not available
  
 
 0.579
DM42_4227
Eps_fam: capsular exopolysaccharide family domain protein
  
 
 0.579
DM42_2959
Conserved hypothetical protein
       0.570
iscU
Nitrogen fixation protein nifu and related proteins; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters
       0.489
DM42_5776
annotation not available
   
 0.486
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
Server load: low (10%) [HD]