node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DM42_2960 | hscB | DM42_2960 | DM42_2965 | Belongs to the low molecular weight phosphotyrosine protein phosphatase family | Fe-s protein assembly co-chaperone hscb; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA | 0.404 |
DM42_2960 | iscA | DM42_2960 | DM42_2964 | Belongs to the low molecular weight phosphotyrosine protein phosphatase family | Iron-sulfur cluster assembly protein isca; Belongs to the HesB/IscA family | 0.449 |
DM42_2960 | iscR | DM42_2960 | DM42_2961 | Belongs to the low molecular weight phosphotyrosine protein phosphatase family | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; iscR: iron-sulfur cluster assembly transcription factor IscR | 0.706 |
DM42_2960 | iscS_2 | DM42_2960 | DM42_2962 | Belongs to the low molecular weight phosphotyrosine protein phosphatase family | Cysteine desulfurase iscs; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins | 0.586 |
DM42_2960 | iscU | DM42_2960 | DM42_2963 | Belongs to the low molecular weight phosphotyrosine protein phosphatase family | Nitrogen fixation protein nifu and related proteins; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters | 0.489 |
IscS | hscA | DM42_4698 | DM42_2966 | annotation not available | Fe-s protein assembly chaperone hsca; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB | 0.543 |
IscS | hscB | DM42_4698 | DM42_2965 | annotation not available | Fe-s protein assembly co-chaperone hscb; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA | 0.739 |
IscS | iscA | DM42_4698 | DM42_2964 | annotation not available | Iron-sulfur cluster assembly protein isca; Belongs to the HesB/IscA family | 0.435 |
IscS | iscR | DM42_4698 | DM42_2961 | annotation not available | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; iscR: iron-sulfur cluster assembly transcription factor IscR | 0.535 |
IscS | iscS | DM42_4698 | DM42_4355 | annotation not available | Cysteine desulfurase iscs; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins | 0.813 |
IscS | iscS_2 | DM42_4698 | DM42_2962 | annotation not available | Cysteine desulfurase iscs; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins | 0.813 |
IscS | iscU | DM42_4698 | DM42_2963 | annotation not available | Nitrogen fixation protein nifu and related proteins; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters | 0.996 |
IscS | iscX | DM42_4698 | DM42_2968 | annotation not available | iscX_yfhJ: FeS assembly protein IscX | 0.526 |
erpA | hscA | DM42_1161 | DM42_2966 | Iron-sulfur cluster assembly accessory family protein; Required for insertion of 4Fe-4S clusters | Fe-s protein assembly chaperone hsca; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB | 0.686 |
erpA | hscB | DM42_1161 | DM42_2965 | Iron-sulfur cluster assembly accessory family protein; Required for insertion of 4Fe-4S clusters | Fe-s protein assembly co-chaperone hscb; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA | 0.832 |
erpA | iscR | DM42_1161 | DM42_2961 | Iron-sulfur cluster assembly accessory family protein; Required for insertion of 4Fe-4S clusters | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; iscR: iron-sulfur cluster assembly transcription factor IscR | 0.530 |
erpA | iscS | DM42_1161 | DM42_4355 | Iron-sulfur cluster assembly accessory family protein; Required for insertion of 4Fe-4S clusters | Cysteine desulfurase iscs; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins | 0.409 |
erpA | iscS_2 | DM42_1161 | DM42_2962 | Iron-sulfur cluster assembly accessory family protein; Required for insertion of 4Fe-4S clusters | Cysteine desulfurase iscs; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins | 0.412 |
erpA | iscU | DM42_1161 | DM42_2963 | Iron-sulfur cluster assembly accessory family protein; Required for insertion of 4Fe-4S clusters | Nitrogen fixation protein nifu and related proteins; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters | 0.698 |
hscA | IscS | DM42_2966 | DM42_4698 | Fe-s protein assembly chaperone hsca; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB | annotation not available | 0.543 |