node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fdx | IscS | DM42_4598 | DM42_4698 | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | annotation not available | 0.748 |
Fdx | cyaY | DM42_4598 | DM42_1435 | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | Iron donor protein cyay; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis | 0.924 |
Fdx | hscA | DM42_4598 | DM42_2966 | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | Fe-s protein assembly chaperone hsca; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB | 0.889 |
Fdx | hscB | DM42_4598 | DM42_2965 | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | Fe-s protein assembly co-chaperone hscb; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA | 0.921 |
Fdx | iscR | DM42_4598 | DM42_2961 | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; iscR: iron-sulfur cluster assembly transcription factor IscR | 0.402 |
Fdx | iscS | DM42_4598 | DM42_4355 | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | Cysteine desulfurase iscs; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins | 0.875 |
Fdx | iscS_2 | DM42_4598 | DM42_2962 | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | Cysteine desulfurase iscs; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins | 0.892 |
Fdx | iscU | DM42_4598 | DM42_2963 | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | Nitrogen fixation protein nifu and related proteins; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters | 0.961 |
IscS | Fdx | DM42_4698 | DM42_4598 | annotation not available | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | 0.748 |
IscS | cyaY | DM42_4698 | DM42_1435 | annotation not available | Iron donor protein cyay; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis | 0.791 |
IscS | fdx | DM42_4698 | DM42_2967 | annotation not available | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | 0.752 |
IscS | hscA | DM42_4698 | DM42_2966 | annotation not available | Fe-s protein assembly chaperone hsca; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB | 0.543 |
IscS | hscB | DM42_4698 | DM42_2965 | annotation not available | Fe-s protein assembly co-chaperone hscb; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA | 0.739 |
IscS | iscR | DM42_4698 | DM42_2961 | annotation not available | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; iscR: iron-sulfur cluster assembly transcription factor IscR | 0.535 |
IscS | iscS | DM42_4698 | DM42_4355 | annotation not available | Cysteine desulfurase iscs; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins | 0.813 |
IscS | iscS_2 | DM42_4698 | DM42_2962 | annotation not available | Cysteine desulfurase iscs; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins | 0.813 |
IscS | iscU | DM42_4698 | DM42_2963 | annotation not available | Nitrogen fixation protein nifu and related proteins; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters | 0.996 |
cyaY | Fdx | DM42_1435 | DM42_4598 | Iron donor protein cyay; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | 0.924 |
cyaY | IscS | DM42_1435 | DM42_4698 | Iron donor protein cyay; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis | annotation not available | 0.791 |
cyaY | fdx | DM42_1435 | DM42_2967 | Iron donor protein cyay; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system | 0.923 |