STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prmB(glutamine-N5) methyltransferase, ribosomal protein L3-specific; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (302 aa)    
Predicted Functional Partners:
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
       0.888
yffB
Transcriptional regulator, spx/mgsr family protein; Belongs to the ArsC family
       0.738
dapD
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family
       0.738
prfA
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
 
 
 0.715
dapC
N-succinyldiaminopimelate aminotransferase; dapC_gpp: succinyldiaminopimelate transaminase
     
 0.687
rsmH
16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
  
 
 0.590
DM42_714
23S rRNA pseudouridine955/2504/2580 synthase; Responsible for synthesis of pseudouridine from uracil
 
  
 0.582
cls
Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
  
    0.568
prmA
Ribosomal protein l11 methyltransferase; Methylates ribosomal protein L11
  
   
 0.555
rlmB
Rna 2'-o ribose methyltransferase substrate binding family protein; Specifically methylates the ribose of guanosine 2251 in 23S rRNA
 
 
 0.514
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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