Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DM42_3138

annotation not available (136 aa)

Predicted Functional Partners:

WI67_05240

0.732

DM42_3137

0.694

WL94_19695

0.532

DM42_3136

0.456

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but resolution at 400 dpi

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_3136	DM42_3137	DM42_3136	DM42_3137	annotation not available	annotation not available	0.644
DM42_3136	DM42_3138	DM42_3136	DM42_3138	annotation not available	annotation not available	0.456
DM42_3137	DM42_3136	DM42_3137	DM42_3136	annotation not available	annotation not available	0.644
DM42_3137	DM42_3138	DM42_3137	DM42_3138	annotation not available	annotation not available	0.694
DM42_3138	DM42_3136	DM42_3138	DM42_3136	annotation not available	annotation not available	0.456
DM42_3138	DM42_3137	DM42_3138	DM42_3137	annotation not available	annotation not available	0.694
DM42_3138	WI67_05240	DM42_3138	DM42_745	annotation not available	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	0.732
DM42_3138	WL94_19695	DM42_3138	DM42_2895	annotation not available	annotation not available	0.532
WI67_05240	DM42_3138	DM42_745	DM42_3138	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	annotation not available	0.732
WL94_19695	DM42_3138	DM42_2895	DM42_3138	annotation not available	annotation not available	0.532

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

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