STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyiHydroxypyruvate isomerase; Belongs to the hyi family (269 aa)    
Predicted Functional Partners:
gcl
Tartronate-semialdehyde synthase; Belongs to the TPP enzyme family
 
 
 0.991
DM42_3221
Tartro_sem_red: 2-hydroxy-3-oxopropionate reductase
 
 
 0.988
DM42_1
D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
  
 
 0.909
ghrB
Glyoxylate/hydroxypyruvate/2-ketogluconate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
  
 
 0.909
ghrB_2
D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
  
 
 0.909
ghrA
annotation not available
    
 0.906
DM42_6879
annotation not available
    
 0.906
DM42_1895
Hpch/hpai aldolase/citrate lyase family protein; Belongs to the HpcH/HpaI aldolase family
     
  0.800
DM42_5592
3-dehydrotetronate 4-kinase; Uncharacterized protein
 
  
 0.579
DM42_5593
annotation not available
 
  
 0.532
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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