node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dnaB | priB | DM42_3231 | DM42_3228 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) | 0.866 |
dnaB | rplB | DM42_3231 | DM42_1470 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome | 0.762 |
dnaB | rplD | DM42_3231 | DM42_1472 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel | 0.637 |
dnaB | rplI | DM42_3231 | DM42_3230 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 50S ribosomal protein L9; Binds to the 23S rRNA | 0.841 |
dnaB | rplV | DM42_3231 | DM42_1468 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome | 0.585 |
dnaB | rpsC | DM42_3231 | DM42_1467 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation | 0.693 |
dnaB | rpsF | DM42_3231 | DM42_3227 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA | 0.676 |
dnaB | rpsJ | DM42_3231 | DM42_1474 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes | 0.430 |
dnaB | rpsR | DM42_3231 | DM42_3229 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit | 0.922 |
priB | dnaB | DM42_3228 | DM42_3231 | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 0.866 |
priB | rplB | DM42_3228 | DM42_1470 | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome | 0.822 |
priB | rplD | DM42_3228 | DM42_1472 | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel | 0.826 |
priB | rplI | DM42_3228 | DM42_3230 | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) | 50S ribosomal protein L9; Binds to the 23S rRNA | 0.961 |
priB | rplV | DM42_3228 | DM42_1468 | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome | 0.864 |
priB | rplW | DM42_3228 | DM42_1471 | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome | 0.818 |
priB | rpsC | DM42_3228 | DM42_1467 | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation | 0.817 |
priB | rpsF | DM42_3228 | DM42_3227 | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA | 0.992 |
priB | rpsJ | DM42_3228 | DM42_1474 | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes | 0.933 |
priB | rpsR | DM42_3228 | DM42_3229 | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit | 0.995 |
rplB | dnaB | DM42_1470 | DM42_3231 | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 0.762 |