WL94_31625 protein (Burkholderia cepacia) - STRING interaction network

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Score

WL94_31625

annotation not available (315 aa)

Predicted Functional Partners:

DM42_3238

0.997

WI67_09910

0.974

arnC

0.972

metG

0.963

WL94_31635

0.961

purN

0.961

folD

0.944

WI67_03825

0.927

WI67_05240

0.924

DM42_6414

0.921

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_3238	WI67_09910	DM42_3238	DM42_3237	annotation not available	annotation not available	0.983
DM42_3238	WL94_31625	DM42_3238	DM42_3239	annotation not available	annotation not available	0.997
DM42_3238	WL94_31635	DM42_3238	DM42_3241	annotation not available	annotation not available	0.973
DM42_3238	arnC	DM42_3238	DM42_3240	annotation not available	annotation not available	0.983
DM42_6414	WL94_31625	DM42_6414	DM42_3239	annotation not available	annotation not available	0.921
DM42_6414	metG	DM42_6414	DM42_2632	annotation not available	Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily	0.866
WI67_03825	WI67_05240	DM42_1023	DM42_745	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	0.931
WI67_03825	WL94_31625	DM42_1023	DM42_3239	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	annotation not available	0.927
WI67_03825	folD	DM42_1023	DM42_2948	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	Bifunctional protein FolD; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	0.984
WI67_03825	metG	DM42_1023	DM42_2632	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily	0.613
WI67_03825	purN	DM42_1023	DM42_2557	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	0.946
WI67_05240	WI67_03825	DM42_745	DM42_1023	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	0.931
WI67_05240	WL94_31625	DM42_745	DM42_3239	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	annotation not available	0.924
WI67_05240	purN	DM42_745	DM42_2557	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	0.912
WI67_09910	DM42_3238	DM42_3237	DM42_3238	annotation not available	annotation not available	0.983
WI67_09910	WL94_31625	DM42_3237	DM42_3239	annotation not available	annotation not available	0.974
WI67_09910	WL94_31635	DM42_3237	DM42_3241	annotation not available	annotation not available	0.956
WI67_09910	arnC	DM42_3237	DM42_3240	annotation not available	annotation not available	0.961
WL94_31625	DM42_3238	DM42_3239	DM42_3238	annotation not available	annotation not available	0.997
WL94_31625	DM42_6414	DM42_3239	DM42_6414	annotation not available	annotation not available	0.921

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