node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LipA | aceF | DM42_3264 | DM42_2952 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | annotation not available | 0.555 |
LipA | acoA | DM42_3264 | DM42_3261 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | ABC transporter substrate-binding protein; Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha | 0.791 |
LipA | acoB | DM42_3264 | DM42_3262 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | Pyruvate dehydrogenase; Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta | 0.906 |
LipA | acoC | DM42_3264 | DM42_3263 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | annotation not available | 0.895 |
LipA | bkdB | DM42_3264 | DM42_477 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | annotation not available | 0.569 |
LipA | sucB | DM42_3264 | DM42_188 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | Dihydrolipoyllysine-residue succinyltransferase, e2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2) | 0.688 |
aceF | LipA | DM42_2952 | DM42_3264 | annotation not available | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | 0.555 |
aceF | acoA | DM42_2952 | DM42_3261 | annotation not available | ABC transporter substrate-binding protein; Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha | 0.917 |
aceF | acoB | DM42_2952 | DM42_3262 | annotation not available | Pyruvate dehydrogenase; Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta | 0.927 |
aceF | acoC | DM42_2952 | DM42_3263 | annotation not available | annotation not available | 0.820 |
aceF | bkdA1 | DM42_2952 | DM42_479 | annotation not available | annotation not available | 0.922 |
aceF | prs | DM42_2952 | DM42_2267 | annotation not available | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P) | 0.815 |
aceF | sucC | DM42_2952 | DM42_2423 | annotation not available | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit | 0.985 |
aceF | sucD | DM42_2952 | DM42_2424 | annotation not available | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit | 0.986 |
acoA | LipA | DM42_3261 | DM42_3264 | ABC transporter substrate-binding protein; Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | 0.791 |
acoA | aceF | DM42_3261 | DM42_2952 | ABC transporter substrate-binding protein; Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha | annotation not available | 0.917 |
acoA | acoB | DM42_3261 | DM42_3262 | ABC transporter substrate-binding protein; Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha | Pyruvate dehydrogenase; Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta | 0.999 |
acoA | acoC | DM42_3261 | DM42_3263 | ABC transporter substrate-binding protein; Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha | annotation not available | 0.992 |
acoA | bkdB | DM42_3261 | DM42_477 | ABC transporter substrate-binding protein; Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha | annotation not available | 0.947 |
acoA | sucB | DM42_3261 | DM42_188 | ABC transporter substrate-binding protein; Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha | Dihydrolipoyllysine-residue succinyltransferase, e2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2) | 0.946 |