node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DM42_202 | engA | DM42_202 | DM42_3292 | Pseudouridine synthase family protein; Belongs to the pseudouridine synthase RsuA family | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 0.780 |
DM42_202 | gidB | DM42_202 | DM42_1686 | Pseudouridine synthase family protein; Belongs to the pseudouridine synthase RsuA family | 16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA | 0.449 |
DM42_202 | rlmN | DM42_202 | DM42_3286 | Pseudouridine synthase family protein; Belongs to the pseudouridine synthase RsuA family | 23S rRNA (adenine2503-C2)-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity | 0.747 |
DM42_202 | rsmH | DM42_202 | DM42_1288 | Pseudouridine synthase family protein; Belongs to the pseudouridine synthase RsuA family | 16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA | 0.494 |
DM42_3287 | engA | DM42_3287 | DM42_3292 | annotation not available | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 0.523 |
DM42_3287 | ndk | DM42_3287 | DM42_3285 | annotation not available | Nucleoside diphosphate kinase family protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate | 0.615 |
DM42_3287 | rlmN | DM42_3287 | DM42_3286 | annotation not available | 23S rRNA (adenine2503-C2)-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity | 0.741 |
DM42_841 | engA | DM42_841 | DM42_3292 | Radical sam superfamily protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 0.462 |
DM42_841 | hflX | DM42_841 | DM42_3294 | Radical sam superfamily protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine | Gtp-binding protein hflx; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis | 0.545 |
DM42_841 | rlmN | DM42_841 | DM42_3286 | Radical sam superfamily protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine | 23S rRNA (adenine2503-C2)-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity | 0.736 |
DM42_841 | rsmH | DM42_841 | DM42_1288 | Radical sam superfamily protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine | 16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA | 0.461 |
engA | DM42_202 | DM42_3292 | DM42_202 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Pseudouridine synthase family protein; Belongs to the pseudouridine synthase RsuA family | 0.780 |
engA | DM42_3287 | DM42_3292 | DM42_3287 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | annotation not available | 0.523 |
engA | DM42_841 | DM42_3292 | DM42_841 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Radical sam superfamily protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine | 0.462 |
engA | gidB | DM42_3292 | DM42_1686 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA | 0.608 |
engA | hflX | DM42_3292 | DM42_3294 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Gtp-binding protein hflx; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis | 0.869 |
engA | ndk | DM42_3292 | DM42_3285 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Nucleoside diphosphate kinase family protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate | 0.469 |
engA | rlmN | DM42_3292 | DM42_3286 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 23S rRNA (adenine2503-C2)-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity | 0.734 |
engA | rsmH | DM42_3292 | DM42_1288 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA | 0.824 |
engA | trmD | DM42_3292 | DM42_756 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Trna (guanine(37)-n(1))-methyltransferase; Specifically methylates guanosine-37 in various tRNAs | 0.542 |