STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
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[Homology]
Score
hpaDhpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase (282 aa)    
Predicted Functional Partners:
hpaE
5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family
 
  
 0.988
DM42_3717
annotation not available
 
  
 0.966
hpaH
hpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase
 
  
 0.945
hpaC
FMN reductase; hpaC: 4-hydroxyphenylacetate 3-monooxygenase, reductase component
 
  
 0.945
DM42_4353
4-hydroxyphenylacetate 3-monooxygenase; 4-hydroxyphenylacetate 3-hydroxylase C terminal family protein
 
  
 0.941
hpcE_1
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; hpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit
 
  
 0.940
HpaG
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; hpaG-N-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit
 
  
 0.938
hpaI
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family
 
  
 0.924
hpaR
MarR family transcriptional regulator; hpaR: homoprotocatechuate degradation operon regulator, HpaR
 
   
 0.917
DM42_6025
annotation not available
  
     0.649
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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