STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcaGProtocatechuate 3,4-dioxygenase, alpha subunit; Plays an essential role in the utilization of numerous aromatic and hydroaromatic compounds via the beta-ketoadipate pathway (197 aa)    
Predicted Functional Partners:
pcaH
Protocatechuate 3,4-dioxygenase, beta subunit; Plays an essential role in the utilization of numerous aromatic and hydroaromatic compounds via the beta-ketoadipate pathway
 0.999
pobA
P-hydroxybenzoate 3-monooxygenase; Pbenz_hydroxyl: 4-hydroxybenzoate 3-monooxygenase
 
 
 0.988
pcaB
protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase
 
  
 0.987
pcaC
decarb_PcaC: 4-carboxymuconolactone decarboxylase
 
  
 0.899
DM42_4393
annotation not available
 
   
 0.789
pcaD
protocat_pcaD: 3-oxoadipate enol-lactonase
 
   
 0.750
DM42_5404
pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family protein
 
   
 0.746
pcaQ
Lysr family transcriptional regulator, pca operon transcriptional activator; Belongs to the LysR transcriptional regulatory family
 
  
 0.692
DM42_5471
annotation not available
 
   
 0.647
DM42_3257
annotation not available
 
   
 0.605
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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