STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_3835annotation not available (293 aa)    
Predicted Functional Partners:
ligD
Bifunctional non-homologous end joining protein ligd; NHEJ_ligase_prk: DNA ligase D
  
 0.949
polA
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
   
 0.942
dnaN
Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...]
    
 0.941
xth
exoDNase_III: exodeoxyribonuclease III
   
 0.674
Xth
exoDNase_III: exodeoxyribonuclease III
   
 0.674
DM42_4863
annotation not available
  
 
 0.639
gmhB
D-glycero-d-manno-heptose 1,7-bisphosphate phosphatase; D,D-heptose 1,7-bisphosphate phosphatase; HAD-SF-IIIA: HAD hydrolase, family IIIA domain protein
    
 0.636
DM42_7140
D-glycero-d-manno-heptose 1,7-bisphosphate phosphatase; HAD-SF-IA-v1: HAD hydrolase, IA, variant 1 family protein
    
 0.636
DM42_4467
Hypothetical protein; Uncharacterized protein
  
     0.594
DM42_3834
sigma70-ECF: RNA polymerase sigma factor, sigma-70 family protein
 
     0.575
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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