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Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Coexpression
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_3897
annotation not available (135 aa)
Predicted Functional Partners:
DM42_3898
annotation not available
0.982
DM42_1638
annotation not available
0.791
WL94_21810
annotation not available
0.743
WL94_30395
annotation not available
0.738
DM42_4803
Phd_fam: prevent-host-death family protein
0.706
WL94_05750
annotation not available
0.705
DM42_4802
annotation not available
0.703
DM42_5995
annotation not available
0.696
DM42_1733
annotation not available
0.654
WI67_03455
Antitoxin; Antitoxin component of a toxin-antitoxin (TA) module
STRING Data Update
