STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
selBselB: selenocysteine-specific translation elongation factor (641 aa)    
Predicted Functional Partners:
rpsB
Small subunit ribosomal protein s2; Belongs to the universal ribosomal protein uS2 family
   
 0.996
selA
L-seryl-trna(ser) seleniumtransferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
 
  
 0.996
hisS
Histidyl-trna synthetase; hisS: histidine--tRNA ligase
   
 0.994
rpsC
Small subunit ribosomal protein s3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
   
 0.991
rplD
Large subunit ribosomal protein l4; Forms part of the polypeptide exit tunnel
   
 0.990
rpsH
Small subunit ribosomal protein s8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
   
 0.988
rpsQ
Small subunit ribosomal protein s17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
   
  0.988
rpsE
Small subunit ribosomal protein s5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
   
 0.985
rpsL
Small subunit ribosomal protein s12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
   
 0.985
rpsD
Small subunit ribosomal protein s4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
   
 0.982
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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