node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DM42_4900 | WI67_14990 | DM42_4900 | DM42_2267 | ribP_PPkin: ribose-phosphate diphosphokinase family protein | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily | 0.837 |
DM42_4900 | guaA | DM42_4900 | DM42_3109 | ribP_PPkin: ribose-phosphate diphosphokinase family protein | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | 0.876 |
DM42_4900 | purF | DM42_4900 | DM42_4088 | ribP_PPkin: ribose-phosphate diphosphokinase family protein | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family | 0.942 |
DM42_4900 | purH | DM42_4900 | DM42_1151 | ribP_PPkin: ribose-phosphate diphosphokinase family protein | Bifunctional purine biosynthesis protein PurH; purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | 0.518 |
DM42_4900 | purL | DM42_4900 | DM42_3186 | ribP_PPkin: ribose-phosphate diphosphokinase family protein | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate | 0.499 |
WI67_14990 | DM42_4900 | DM42_2267 | DM42_4900 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily | ribP_PPkin: ribose-phosphate diphosphokinase family protein | 0.837 |
WI67_14990 | guaA | DM42_2267 | DM42_3109 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | 0.891 |
WI67_14990 | purF | DM42_2267 | DM42_4088 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family | 0.950 |
WI67_14990 | purH | DM42_2267 | DM42_1151 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily | Bifunctional purine biosynthesis protein PurH; purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | 0.687 |
WI67_14990 | purL | DM42_2267 | DM42_3186 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate | 0.499 |
WI67_14990 | purM | DM42_2267 | DM42_1077 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily | purM: phosphoribosylformylglycinamidine cyclo-ligase | 0.407 |
carA | carB | DM42_431 | DM42_429 | CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | 0.999 |
carA | guaA | DM42_431 | DM42_3109 | CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | 0.729 |
carA | purD | DM42_431 | DM42_2766 | CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family | purD: phosphoribosylamine--glycine ligase; Belongs to the GARS family | 0.620 |
carA | purF | DM42_431 | DM42_4088 | CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family | 0.960 |
carA | purH | DM42_431 | DM42_1151 | CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family | Bifunctional purine biosynthesis protein PurH; purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | 0.559 |
carA | purL | DM42_431 | DM42_3186 | CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate | 0.595 |
carA | purM | DM42_431 | DM42_1077 | CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family | purM: phosphoribosylformylglycinamidine cyclo-ligase | 0.566 |
carB | carA | DM42_429 | DM42_431 | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family | 0.999 |
carB | guaA | DM42_429 | DM42_3109 | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | 0.940 |